Publications

For an overview of the Hawke Lab research, click [p59-61_Dr_Thomas_Hawke.pdf] for our highlighted article in International Innovation Magazine!

Refereed papers

(A) Publications in peer-reviewed journals (20 most recent here- for complete list click here to go to Pubmed)

1: vanLieshout TL, Stouth DW, Hartel NG, Vasam G, Ng SY, Webb EK, Rebalka IA,
Mikhail AI, Graham NA, Menzies KJ, Hawke TJ, Ljubicic V. The CARM1 transcriptome
and arginine methylproteome mediate skeletal muscle integrative biology. Mol
Metab. 2022 Oct;64:101555. doi: 10.1016/j.molmet.2022.101555. Epub 2022 Jul 21.
PMID: 35872306; PMCID: PMC9379683.

2: Turner LV, MacDonald MJ, Riddell MC, Voth J, Hawke TJ. Decreased Diastolic
Blood Pressure and Average Grip Strength in Adults With Type 1 Diabetes Compared
With Controls: An Analysis of Data From the Canadian Longitudinal Study on
Aging. Can J Diabetes. 2022 Dec;46(8):789-796. doi: 10.1016/j.jcjd.2022.05.005.
Epub 2022 May 27. PMID: 35835668.

3: Travis C, Srivastava PS, Hawke TJ, Kalaitzoglou E. Diabetic Bone Disease and
Diabetic Myopathy: Manifestations of the Impaired Muscle-Bone Unit in Type 1
Diabetes. J Diabetes Res. 2022 May 12;2022:2650342. doi: 10.1155/2022/2650342.
PMID: 35601019; PMCID: PMC9119786.

4: Hawke TJ. Do those with type 1 diabetes need more exercise to maintain
skeletal muscle health? J Physiol. 2022 Mar;600(6):1281-1282. doi:
10.1113/JP282800. Epub 2022 Feb 25. PMID: 35167704.

5: Dial AG, Grafham GK, Monaco CMF, Voth J, Brandt L, Tarnopolsky MA, Hawke TJ.
Alterations in skeletal muscle repair in young adults with type 1 diabetes
mellitus. Am J Physiol Cell Physiol. 2021 Nov 1;321(5):C876-C883. doi:
10.1152/ajpcell.00322.2021. Epub 2021 Sep 29. PMID: 34586898.

6: Monaco CMF, Tarnopolsky MA, Dial AG, Nederveen JP, Rebalka IA, Nguyen M,
Turner LV, Perry CGR, Ljubicic V, Hawke TJ. Normal to enhanced intrinsic
mitochondrial respiration in skeletal muscle of middle- to older-aged women and
men with uncomplicated type 1 diabetes. Diabetologia. 2021 Nov;64(11):2517-2533.
doi: 10.1007/s00125-021-05540-1. Epub 2021 Aug 14. PMID: 34392397.

7: Dial AG, Monaco CMF, Grafham GK, Patel TP, Tarnopolsky MA, Hawke TJ. Impaired
Function and Altered Morphology in the Skeletal Muscles of Adult Men and Women
With Type 1 Diabetes. J Clin Endocrinol Metab. 2021 Jul 13;106(8):2405-2422.
doi: 10.1210/clinem/dgab261. PMID: 33890059.

8: Hawke TJ. Expanding Roles for Muscle Satellite Cells in Exercise-Induced
Hypertrophy. Function (Oxf). 2020 Dec 15;2(1):zqaa040. doi:
10.1093/function/zqaa040. PMID: 35330976; PMCID: PMC8788736.

9: Dial AG, Monaco CMF, Grafham GK, Romanova N, Simpson JA, Tarnopolsky MA,
Perry CGR, Kalaitzoglou E, Hawke TJ. Muscle and serum myostatin expression in
type 1 diabetes. Physiol Rep. 2020 Jul;8(13):e14500. doi: 10.14814/phy2.14500.
PMID: 32652899; PMCID: PMC7354085.

10: Lu JQ, Monaco CMF, Hawke TJ, Yan C, Tarnopolsky MA. Increased intra-
mitochondrial lipofuscin aggregates with spherical dense body formation in
mitochondrial myopathy. J Neurol Sci. 2020 Jun 15;413:116816. doi:
10.1016/j.jns.2020.116816. Epub 2020 Apr 1. PMID: 32272361.

11: Schweitzer AM, Gingrich MA, Hawke TJ, Rebalka IA. The impact of statins on
physical activity and exercise capacity: an overview of the evidence,
mechanisms, and recommendations. Eur J Appl Physiol. 2020 Jun;120(6):1205-1225.
doi: 10.1007/s00421-020-04360-2. Epub 2020 Apr 4. PMID: 32248287.

12: Monaco CMF, Perry CGR, Hawke TJ. Alterations in mitochondrial functions and
morphology in muscle and non-muscle tissues in type 1 diabetes: implications for
metabolic health. Exp Physiol. 2020 Apr;105(4):565-570. doi: 10.1113/EP088096.
Epub 2020 Jan 9. PMID: 31826331.

13: Monaco CMF, Bellissimo CA, Hughes MC, Ramos SV, Laham R, Perry CGR, Hawke
TJ. Sexual dimorphism in human skeletal muscle mitochondrial bioenergetics in
response to type 1 diabetes. Am J Physiol Endocrinol Metab. 2020 Jan
1;318(1):E44-E51. doi: 10.1152/ajpendo.00411.2019. Epub 2019 Dec 3. PMID:
31794260; PMCID: PMC6985789.

14: Rebalka IA, Cao AW, May LL, Tarnopolsky MA, Hawke TJ. Statin administration
activates system xC^- in skeletal muscle: a potential mechanism
explaining statin-induced muscle pain. Am J Physiol Cell Physiol. 2019 Nov
1;317(5):C894-C899. doi: 10.1152/ajpcell.00308.2019. Epub 2019 Sep 11. PMID:
31509447; PMCID: PMC6879878.

15: Hughes MC, Ramos SV, Turnbull PC, Rebalka IA, Cao A, Monaco CMF, Varah NE,
Edgett BA, Huber JS, Tadi P, Delfinis LJ, Schlattner U, Simpson JA, Hawke TJ,
Perry CGR. Early myopathy in Duchenne muscular dystrophy is associated with
elevated mitochondrial H₂ O₂ emission during impaired
oxidative phosphorylation. J Cachexia Sarcopenia Muscle. 2019 Jun;10(3):643-661.
doi: 10.1002/jcsm.12405. Epub 2019 Apr 2. PMID: 30938481; PMCID: PMC6596403.

16: Krause MP, Milne KJ, Hawke TJ. Adiponectin-Consideration for its Role in
Skeletal Muscle Health. Int J Mol Sci. 2019 Mar 27;20(7):1528. doi:
10.3390/ijms20071528. PMID: 30934678; PMCID: PMC6480271.

17: Monaco CMF, Gingrich MA, Hawke TJ. Considering Type 1 Diabetes as a Form of
Accelerated Muscle Aging. Exerc Sport Sci Rev. 2019 Apr;47(2):98-107. doi:
10.1249/JES.0000000000000184. PMID: 30653028.

18: Manta A, Stouth DW, Xhuti D, Chi L, Rebalka IA, Kalmar JM, Hawke TJ,
Ljubicic V. Chronic exercise mitigates disease mechanisms and improves muscle
function in myotonic dystrophy type 1 mice. J Physiol. 2019
Mar;597(5):1361-1381. doi: 10.1113/JP277123. Epub 2019 Jan 30. PMID: 30628727;
PMCID: PMC6395422.

19: Rebalka IA, Monaco CMF, Varah NE, Berger T, D’souza DM, Zhou S, Mak TW,
Hawke TJ. Loss of the adipokine lipocalin-2 impairs satellite cell activation
and skeletal muscle regeneration. Am J Physiol Cell Physiol. 2018 Nov
1;315(5):C714-C721. doi: 10.1152/ajpcell.00195.2017. Epub 2018 Sep 26. PMID:
30257107; PMCID: PMC6293054.

20: Monaco CMF, Hughes MC, Ramos SV, Varah NE, Lamberz C, Rahman FA, McGlory C,
Tarnopolsky MA, Krause MP, Laham R, Hawke TJ, Perry CGR. Altered mitochondrial
bioenergetics and ultrastructure in the skeletal muscle of young adults with
type 1 diabetes. Diabetologia. 2018 Jun;61(6):1411-1423. doi:
10.1007/s00125-018-4602-6. Epub 2018 Apr 18. Erratum in: Diabetologia. 2020
Apr;63(4):887-888. PMID: 29666899.